PRKCZ monoclonal antibody, clone S19-V (FITC)
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human PRKCZ.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
EVAC purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (10 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with PRKCZ monoclonal antibody, clone S19-V (FITC) (Cat # MAB15996). -
Gene Info — PRKCZ
Entrez GeneID
5590Protein Accession#
Q05513Gene Name
PRKCZ
Gene Alias
PKC-ZETA, PKC2
Gene Description
protein kinase C, zeta
Omim ID
176982Gene Ontology
HyperlinkGene Summary
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000001368|OTTHUMP00000044160
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