LAMB3 monoclonal antibody, clone CL3353
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human lung tissue lysate with LAMB3 monoclonal antibody, clone CL3353 (Cat # MAB15799).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with LAMB3 monoclonal antibody, clone CL3353 (Cat # MAB15799) shows immunoreactivity in basement membrane of glandular epithelium.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human LAMB3.
Immunogen
Recombinant protein corresponding to human LAMB3.
Epitope
This antibody binds to an epitope located within the peptide sequence ASEQALSAQEGFERI as determined by overlapping synthetic peptides.
Sequence
KLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQ
Host
Mouse
Reactivity
Human, Rat
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human lung tissue lysate with LAMB3 monoclonal antibody, clone CL3353 (Cat # MAB15799).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with LAMB3 monoclonal antibody, clone CL3353 (Cat # MAB15799) shows immunoreactivity in basement membrane of glandular epithelium. -
Gene Info — LAMB3
Entrez GeneID
3914Protein Accession#
Q13751Gene Name
LAMB3
Gene Alias
BM600-125KDA, FLJ99565, LAM5, LAMNB1
Gene Description
laminin, beta 3
Gene Ontology
HyperlinkGene Summary
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034555|OTTHUMP00000034640|kalinin B1 chain|kalinin-140kDa|laminin B1k chain|laminin S B3 chain|laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD))|nicein-125kDa
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Interactome
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Pathway
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Disease
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