KRT8 monoclonal antibody, clone AT3D11
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate using KRT8 monoclonal antibody, clone AT3D11 (Cat # MAB12471) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with KRT8 monoclonal antibody, clone AT3D11 (Cat # MAB12471) under 10 ug/mL working concentration.
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human KRT8.
Immunogen
Recombinant protein corresponding to full length human KRT8.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG3, kappa
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate using KRT8 monoclonal antibody, clone AT3D11 (Cat # MAB12471) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with KRT8 monoclonal antibody, clone AT3D11 (Cat # MAB12471) under 10 ug/mL working concentration.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KRT8
Entrez GeneID
3856Protein Accession#
P05787Gene Name
KRT8
Gene Alias
CARD2, CK8, CYK8, K2C8, K8, KO
Gene Description
keratin 8
Gene Ontology
HyperlinkGene Summary
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
Other Designations
cytokeratin 8|keratin, type II cytoskeletal 8
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Interactome
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Disease
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