TYR monoclonal antibody, clone T311
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Specification
Product Description
Mouse monoclonal antibody raised against TYR.
Immunogen
Recombinant protein corresponding to human TYR.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG2a Kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human melanoma with TYR monoclonal antibody, clone T311 (Cat # MAB11267) at 1:200 dilution.Immunohistochemistry (Frozen sections)
Immunocytochemistry
Immunofluorescence
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Gene Info — TYR
Entrez GeneID
7299Protein Accession#
NP_000363Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactome
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Pathway
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Disease
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