SENP7 monoclonal antibody (M01), clone 2D4

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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SENP7.
Immunogen
SENP7 (NP_065705, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSRSSPERIPRVILTNVLGTELG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (72)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SENP7 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SENP7
Entrez GeneID
57337GeneBank Accession#
NM_020654Protein Accession#
NP_065705Gene Name
SENP7
Gene Alias
KIAA1707, MGC157730
Gene Description
SUMO1/sentrin specific peptidase 7
Gene Ontology
HyperlinkGene Summary
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM
Other Designations
SUMO1/sentrin specific protease 7|sentrin/SUMO-specific protease|sentrin/SUMO-specific protease 7
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