Products

Western Blot (Cell lysate)

KLK8 monoclonal antibody (M01), clone 2F11 Western Blot analysis of KLK8 expression in A-431 ( Cat # L015V1 ).

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged KLK8 is approximately 0.3ng/ml as a capture antibody.

ELISA

Immunofluorescence

Immunofluorescence of monoclonal antibody to KLK8 on A-431 cell. [antibody concentration 10 ug/ml]

Entrez GeneID

11202

GeneBank Accession#

NM_007196

Protein Accession#

NP_009127

Gene Name

KLK8

Gene Alias

HNP, NP, NRPN, PRSS19, TADG14

Gene Description

kallikrein-related peptidase 8

Omim ID

605644

Gene Ontology

Hyperlink

Gene Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq

Other Designations

KLK8 protein type 1|KLK8 protein type 2|kallikrein 8|kallikrein 8 (neuropsin/ovasin)|neuropsin type 1|neuropsin type 2|ovasin|protease, serine, 19|tumor-associated differentially expressed gene 14