MAGI2 monoclonal antibody (M01), clone 6C8

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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAGI2.
Immunogen
MAGI2 (NP_036433, 519 a.a. ~ 628 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPTDGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (97)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAGI2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — MAGI2
Entrez GeneID
9863GeneBank Accession#
NM_012301Protein Accession#
NP_036433Gene Name
MAGI2
Gene Alias
ACVRIP1, AIP1, ARIP1, MAGI-2, SSCAM
Gene Description
membrane associated guanylate kinase, WW and PDZ domain containing 2
Omim ID
606382Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq
Other Designations
activin receptor interacting protein 1|atrophin 1 interacting protein 1|atrophin-1 interacting protein A|membrane associated guanylate kinase 2
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Interactome
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Pathway
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Disease
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