BCOR Split FISH Probe
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More Files
- More Functions
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: BCOR
Size: Approximately 350kb
Fluorophore: TexRed
Location: Xp11.4Probe 2
Name: BCOR
Size: Approximately 430kb
Fluorophore: FITC
Location: Xp11.4Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
Fluorescent In Situ Hybridization (Cell)
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Gene Info — BCOR
Entrez GeneID
54880Gene Name
BCOR
Gene Alias
ANOP2, FLJ20285, FLJ38041, KIAA1575, MAA2, MCOPS2, MGC131961, MGC71031
Gene Description
BCL6 co-repressor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
5830466J11Rik|8430401K06Rik|BCL-6 interacting corepressor|OTTHUMP00000025766|OTTHUMP00000025768
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Interactome
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Publication Reference
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High-grade Endometrial Stromal Sarcoma: Morphologic and Clinical Features, the Role of Immunohistochemistry and Fluorescence in Situ Hybridization in Diagnosis.
Nazli Eylem Alkanat, Aysegul Uner, Alp Usubutun.
International Journal of Surgical Pathology 2022 May; [Epub].
Application：FISH, Human, Uterine sarcomas tumor.
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A Case Series of BCOR Sarcomas With a New Splice Variant of BCOR/CCNB3 Fusion Gene.
Anastasios Kyriazoglou, Natalia Tourkantoni, Michalis Liontos, Flora Zagouri, Louisa Mahaira, Alexandra Papakosta, Dimitra Michali, Amalia Patereli, Kalliopi Stefanaki, Vasiliki Tzotzola, Evangelia Skoura, Margarita Baka, Sofia Polychronopoulou, Antonis Kattamis, Efthymios Dimitriadis.
In Vivo (Athens, Greece) 2020 Sep; 4(5):2947.
Application：FISH, Human, Human Ewing-like sarcoma.
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High-grade Endometrial Stromal Sarcoma: Morphologic and Clinical Features, the Role of Immunohistochemistry and Fluorescence in Situ Hybridization in Diagnosis.
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