HSP90AA1/CEN14q FISH Probe

Catalog # FG0267

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Size:200 uL
Price: USD $ 2,070.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
QC Test

Hybridization position of the probes on the chromosome.
Note

Hybridization position of the probes on the chromosome.

Hybridization position of the probes on the chromosome.

  • Specification

    Product Description

    Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).

    Probe 1

    Name: HSP90AA1
    Size: Approximately 380kb
    Fluorophore: Texas Red
    Location: 14q32.31

    Probe 2

    Name: CEN14q
    Size: Approximately 400kb
    Fluorophore: FITC
    Location: 14q12

    Origin

    Human

    Source

    Genomic DNA

    Form

    Liquid

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulatory Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Storage Instruction

    Store at 4°C in the dark.

    Note

    Hybridization position of the probes on the chromosome.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

  • Gene Info — HSP90AA1

    Entrez GeneID

    3320

    Gene Name

    HSP90AA1

    Gene Alias

    FLJ31884, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2

    Gene Description

    heat shock protein 90kDa alpha (cytosolic), class A member 1

    Omim ID

    140571

    Gene Ontology

    Hyperlink

    Gene Summary

    HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM

    Other Designations

    heat shock 90kD protein 1, alpha|heat shock 90kD protein 1, alpha-like 4|heat shock 90kD protein, alpha-like 4|heat shock 90kDa protein 1, alpha

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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