EPOR polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant EPOR.
Immunogen
EPOR (NP_000112, 31 a.a. ~ 130 a.a) partial recombinant protein with GST tag.
Sequence
PDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — EPOR
Entrez GeneID
2057GeneBank Accession#
NM_000121Protein Accession#
NP_000112Gene Name
EPOR
Gene Alias
MGC138358
Gene Description
erythropoietin receptor
Gene Ontology
HyperlinkGene Summary
The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq
Other Designations
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Effect of pentavalent inorganic arsenic salt on erythropoietin production and autophagy induction.
Kazuhiko Nishimura, Naotake Kiriyama, Kazuya Ogawa, Reo Inoue, Md Anamul Haque, Hiroshi Nakagawa.
Archives of Biochemistry and Biophysics 2023 Jan; 734:109487.
Application:WB-Tr, Human, HepG2 cells.
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Effect of pentavalent inorganic arsenic salt on erythropoietin production and autophagy induction.
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