FCER2 monoclonal antibody, clone Tu1
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Specification
Product Description
Mouse monoclonal antibody raised against full length native FCER2.
Immunogen
Native purified FCER2 from human Tonsil lymphocytes.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to FCEP2.
Form
Liquid
Isotype
IgG3
Recommend Usage
Flow cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — FCER2
Entrez GeneID
2208Gene Name
FCER2
Gene Alias
CD23, CD23A, CLEC4J, FCE2, IGEBF
Gene Description
Fc fragment of IgE, low affinity II, receptor for (CD23)
Omim ID
151445Gene Ontology
HyperlinkGene Summary
The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.[supplied by OMIM
Other Designations
C-type lectin domain family 4, member J|CD23 antigen|Fc fragment of IgE, low affinity II, receptor for (CD23A)
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Interactome
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Pathway
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Disease
- Asthma
- Birth Weight
- Bronchiolitis
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Infant
- Leukemia
- Lung Neoplasms
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Publication Reference
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A new role for CD23 in inflammation.
Bonnefoy JY, Plater-Zyberk C, Lecoanet-Henchoz S, Gauchat JF, Aubry JP, Graber P.
Immunology Today 1996 Sep; 17(9):418.
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Regulation of IgE synthesis. Lessons from the study of IgE transgenic and CD23-deficient mice.
Lamers MC, Yu P.
Immunological Reviews 1995 Dec; 148:71.
Application:Flow Cyt, Mouse, Mouse B lymphocytes.
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CD23 and B-cell activation.
Bonnefoy JY, Lecoanet-Henchoz S, Aubry JP, Gauchat JF, Graber P.
Current Opinion in Immunology 1995 Jun; 7(3):355.
Application:Flow Cyt, Human, Mouse, T cells.
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CD23: novel disease marker with a split personality.
Gordon J.
Clinical and Experimental Immunology 1991 Dec; 86(3):356.
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A new role for CD23 in inflammation.
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