miRNA probes are short RNA molecules used to identify and localize microRNAs (miRNAs) present in biological samples. They are designed to be complementary to the target miRNA sequence, allowing them to form a stable duplex with the miRNA and facilitating the detection and quantification of miRNAs. With our state-of-the-art custom miRNA probe service, Abnova offers you the power to design and tailor high-quality miRNA probes specific to your research needs.

Custom_miRNA_Probes.pdf

Advantages
  • High specificity and minimal cross-reactivity
  • Suitable for analyzing samples with limited miRNA content
  • Possible to use cell, frozen tissue, or FFPE tissue samples 
  • Visualize the distribution and localization of specific miRNA
  • Semi-quantify the expression levels of miRNA
 
 

Applications
  • Gene regulation studies
  • Functional analysis
  • miRNA expression profiling
  • Diagnostic biomarker discovery
  • Drug discovery and development
 
 

Flowchart
miRNA-Probe_flow.png (30 KB)
 
 
 

Examples

Chromogenic In Situ Hybridization (CISH)
 
CISH_Data.png (219 KB)
 
Detection of miR-122-5p by chromogenic in situ hybridization in formalin-fixed, paraffin-embedded human liver tissues.
 
 

Fluorescence In Situ Hybridization (FISH)
 
FISH_Data.png (69 KB)
 
Detection of hsa-miR-122-5p by fluorescence in situ hybridization in Hepa1-6 cells.
 
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