ADRBK2 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant ADRBK2.
Immunogen
Recombinant protein corresponding to amino acids of human ADRBK2.
Sequence
YEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with ADRBK2 polyclonal antibody (Cat # PAB19998) shows strong nuclear positivity in exocrine glandular cells at 1:200-1:500 dilution. -
Gene Info — ADRBK2
Entrez GeneID
157Protein Accession#
P35626Gene Name
ADRBK2
Gene Alias
BARK2, GRK3
Gene Description
adrenergic, beta, receptor kinase 2
Omim ID
109636Gene Ontology
HyperlinkGene Summary
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq
Other Designations
beta adrenergic receptor kinase 2
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Interactomes
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Pathways
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Diseases
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