ZEB1 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of ZEB1.
Immunogen
A synthetic peptide corresponding to 15 amino acids near internal region of human ZEB1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunocytochemistry (20 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ZEB1 in HeLa cell lysate with ZEB1 polyclonal antibody (Cat # PAB19268) at 1ug/mL.Immunocytochemistry
Immunocytochemistry of HeLa cells with ZEB1 polyclonal antibody (Cat # PAB19268) at 20 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ZEB1
Entrez GeneID
6935Protein Accession#
CAI12550Gene Name
ZEB1
Gene Alias
AREB6, BZP, DELTA-EF1, MGC133261, NIL-2-A, NIL-2A, NIL2A, TCF8, ZEB, ZFHEP, ZFHX1A
Gene Description
zinc finger E-box binding homeobox 1
Gene Ontology
HyperlinkGene Summary
ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM
Other Designations
OTTHUMP00000019405|transcription factor 8 (represses interleukin 2 expression)|zinc finger homeodomain enhancer-binding protein
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Interactomes
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Diseases
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Publication Reference
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A Novel Calcium-Mediated EMT Pathway Controlled by Lipids: An Opportunity for Prostate Cancer Adjuvant Therapy.
Figiel S, Bery F, Chantôme A, Fontaine D, Pasqualin C, Maupoil V, Domingo I, Guibon R, Bruyère F, Potier-Cartereau M, Vandier C, Fromont G, Mahéo K.
Cancers 2019 Nov; 11(11):E1814.
Application:IHC-P, Human, DU145 cells, Human prostate cancer.
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Clinical significance of epithelial-mesenchymal transition (EMT) markers in prostate cancer.
Figiel S, Vasseur C, Bruyere F, Rozet F, Maheo K, Fromont G.
Human Pathology 2017 Mar; 61:26.
Application:IHC-P, Human, Human prostate.
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A Novel Calcium-Mediated EMT Pathway Controlled by Lipids: An Opportunity for Prostate Cancer Adjuvant Therapy.
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