CDKN1C polyclonal antibody

Catalog # PAB18370

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Size:100 ug
Price: USD $ 346.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of extracts from K-562 cells, using CDKN1C polyclonal antibody (Cat # PAB18370).
Peptide "+" means "peptide blocking".

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of CDKN1C.

    Immunogen

    A synthetic peptide corresponding to residues surrounding T310 of human CDKN1C.

    Host

    Rabbit

    Reactivity

    Human, Mouse

    Specificity

    This antibody is specific to CDKN1C.

    Form

    Liquid

    Purification

    Affinity purification

    Concentration

    1 mg/mL

    Recommend Usage

    Western Blot (1:500-1:1000)
    Immunofluorescence (1:500-1:1000)
    ELISA (1:5000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of extracts from K-562 cells, using CDKN1C polyclonal antibody (Cat # PAB18370).
    Peptide "+" means "peptide blocking".

    Immunofluorescence

    Enzyme-linked Immunoabsorbent Assay

  • Gene Info — CDKN1C

    Entrez GeneID

    1028

    Protein Accession#

    P49918

    Gene Name

    CDKN1C

    Gene Alias

    BWCR, BWS, KIP2, WBS, p57

    Gene Description

    cyclin-dependent kinase inhibitor 1C (p57, Kip2)

    Omim ID

    130650 600856

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000011736|cyclin-dependent kinase inhibitor 1C

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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