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Last updated: 2023/3/19

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FKBP5 monoclonal antibody, clone AFBE-6 

  • Catalog # : MAB22309
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic protein of human FKBP5.
  • Immunogen:
  • A synthetic peptide corresponding to human FKBP5.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody reacts with human, rat FKBP5, in native form and recombinant. Superfamily members of FKBP5 are not reactive to antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (cell lysate) analysis of Caco-2 cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2289
  • Gene Name:
  • FKBP5
  • Gene Alias:
  • FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10
  • Gene Description:
  • FK506 binding protein 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq
  • Other Designations:
  • 51 kDa FK506-binding protein 5,54 kDa progesterone receptor-associated immunophilin,FF1 antigen,FK506-binding protein 5,HSP90-binding immunophilin,OTTHUMP00000016268,T-cell FK506-binding protein,peptidylprolyl cis-trans isomerase,rotamase
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