Rabbit monoclonal antibody raised against synthetic protein of human SERPINC1.
Immunogen:
A synthetic peptide corresponding to human SERPINC1.
Host:
Rabbit
Reactivity:
Human
Specificity:
This antibody reacts with human SERPINC1, in native form and recombinant. Superfamily members of SERPINC1 are not reactive to antibody.
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
Immunofluorescence (1:50-200) Immunocytochemistry (1:50-200) Western Blot (1:500-2000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations:
OTTHUMP00000035393,antithrombin (aa 375-432),antithrombin III,coding sequence signal peptide antithrombin part 1,serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1,signal peptide antithrombin part 1