EPHA2 monoclonal antibody, clone 1B3C7
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant EPHA2.
Immunogen
Recombinant protein corresponding to human EPHA2.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgM
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using EPHA2 monoclonal antibody, clone 1B3C7 (Cat # MAB10635) against NIH/3T3 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human skin carcinoma (upper) and pancreas carcinoma (bottom) tissue, showing cytoplasmic localization using EPHA2 monoclonal antibody, clone 1B3C7 (Cat # MAB10635) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EPHA2
Entrez GeneID
1969Gene Name
EPHA2
Gene Alias
ECK
Gene Description
EPH receptor A2
Omim ID
176946Gene Ontology
HyperlinkGene Summary
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. [provided by RefSeq
Other Designations
ephrin receptor EphA2|epithelial cell receptor protein tyrosine kinase|protein tyrosine kinase|receptor protein tyrosine kinase regulated by p53 and E2F-1|soluble EPHA2 variant 1
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Interactomes
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Pathways
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Diseases
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