AGER monoclonal antibody, clone YK-2B4
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant AGER.
Immunogen
Recombinant protein corresponding to excellular domain of human AGER.
Host
Mouse
Theoretical MW (kDa)
46-54
Reactivity
Human
Form
Liquid
Purification
Protein A-Sepharose chromatography
Concentration
1.0 mg/mL
Isotype
IgG1
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM PBS, pH 7.5, 300 mM NaCl (50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Transfected lysate)
Western blot analysis of AGER expression in AGER/HEK 293 (1), and HEK293 (2) cell linesFlow Cytometry
Flow cytometric analysis of AGER in AGER/HEK 293, and HEK293 cell lines. -
Gene Info — AGER
Entrez GeneID
177Gene Name
AGER
Gene Alias
MGC22357, RAGE
Gene Description
advanced glycosylation end product-specific receptor
Omim ID
600214Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029155|OTTHUMP00000029156|advanced glycosylation end product-specific receptor RAGE3|advanced glycosylation end product-specific receptor variant sRAGE1|advanced glycosylation end product-specific receptor variant sRAGE2|receptor for advanced
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Interactomes
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Diseases
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