PIP5K3 monoclonal antibody (M02), clone 1D11
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant PIP5K3.
Immunogen
PIP5K3 (NP_689884, 342 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKGRR
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PIP5K3 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — PIP5K3
Entrez GeneID
200576GeneBank Accession#
NM_152671Protein Accession#
NP_689884Gene Name
PIP5K3
Gene Alias
CFD, FAB1, KIAA0981, MGC40423, PIKFYVE, PIP5K
Gene Description
phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
Gene Ontology
HyperlinkGene Summary
PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes, including membrane trafficking and cytoskeletal reorganization (Shisheva et al., 1999 [PubMed 9858586]).[supplied by OMIM
Other Designations
1-phosphatidylinositol-4-phosphate 5-kinase|FYVE finger-containing phosphoinositide kinase|OTTHUMP00000163872|PtdIns(4)P-5-kinase|phosphatidylinositol-3-phosphate 5-kinase type III|phosphatidylinositol-4-phosphate 5-kinase, type III
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Interactomes
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Pathways
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Diseases
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