CENTD2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CENTD2 partial ORF ( AAH56401, 101 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DFERLGRLPYKAGLSLQRAQEGWFSLSGSELRAVFPEGPCEEPLQLRKLQELSIQGDSENQVLVLVERRRTLYIQGERRLDFMGWLGAIQKAAASMGDTL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ARAP1
Entrez GeneID
116985GeneBank Accession#
BC056401Protein Accession#
AAH56401Gene Name
ARAP1
Gene Alias
CENTD2, KIAA0782
Gene Description
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Omim ID
606646Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1|centaurin, delta 2
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Interactome
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Pathway
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