BSCL2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
BSCL2 MaxPab rabbit polyclonal antibody. Western Blot analysis of BSCL2 expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of BSCL2 expression in transfected 293T cell line (H00026580-T01) by BSCL2 MaxPab polyclonal antibody.
Lane 1: BSCL2 transfected lysate(44.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human BSCL2 protein.
Immunogen
BSCL2 (AAH09866.2, 1 a.a. ~ 400 a.a) full-length human protein.
Sequence
MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGAGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BSCL2 MaxPab rabbit polyclonal antibody. Western Blot analysis of BSCL2 expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of BSCL2 expression in transfected 293T cell line (H00026580-T01) by BSCL2 MaxPab polyclonal antibody.
Lane 1: BSCL2 transfected lysate(44.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BSCL2
Entrez GeneID
26580GeneBank Accession#
BC009866.2Protein Accession#
AAH09866.2Gene Name
BSCL2
Gene Alias
GNG3LG, HMN5, MGC4694, SPG17
Gene Description
Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
Gene Ontology
HyperlinkGene Summary
This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
seipin
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Interactome
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Disease
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Publication Reference
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Alleviation of seipinopathy-related ER stress by triglyceride storage.
Holtta-Vuori M, Salo VT, Ohsaki Y, Suster ML, Ikonen E.
Human Molecular Genetics 2012 Dec; 22(6):1157.
Application：WB-Ce, IF, Human, U251MG cells.
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Alleviation of seipinopathy-related ER stress by triglyceride storage.
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