LTA purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human LTA protein.
Immunogen
LTA (AAH34729.1, 1 a.a. ~ 205 a.a) full-length human protein.
Sequence
MTPPERLFLPRVRGTTLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of LTA expression in transfected 293T cell line (H00004049-T01) by LTA MaxPab polyclonal antibody.
Lane 1: LTA transfected lysate(22.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — LTA
Entrez GeneID
4049GeneBank Accession#
BC034729Protein Accession#
AAH34729.1Gene Name
LTA
Gene Alias
LT, TNFB, TNFSF1
Gene Description
lymphotoxin alpha (TNF superfamily, member 1)
Omim ID
153440Gene Ontology
HyperlinkGene Summary
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
Other Designations
OTTHUMP00000029184|OTTHUMP00000037612|OTTHUMP00000037613|OTTHUMP00000165897|lymphotoxin alpha|tumor necrosis factor beta
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Abnormal gene and protein expression of inflammatory cytokines in the postmortem brain of schizophrenia patients.
Pandey GN, Rizavi HS, Zhang H, Ren X.
Schizophrenia Research 2017 May; [Epub].
Application:WB-Ti, Human, Brain from schizophrenia patients and health control.
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Targeted inhibition of phosphatidyl inositol-3-kinase p110β, but not p110α, enhances apoptosis and sensitivity to paclitaxel in chemoresistant ovarian cancers.
Jeong JY, Kim KS, Moon JS, Song JA, Choi SH, Kim KI, Kim TH, An HJ.
Apoptosis 2013 Apr; 18(4):509.
Application:WB, Human, SKOV3, Skpac, A2780.
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Abnormal gene and protein expression of inflammatory cytokines in the postmortem brain of schizophrenia patients.
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