KRT1 monoclonal antibody (M01), clone 2A7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KRT1.
Immunogen
KRT1 (NP_006112, 387 a.a. ~ 496 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KRT1 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — KRT1
Entrez GeneID
3848GeneBank Accession#
NM_006121Protein Accession#
NP_006112Gene Name
KRT1
Gene Alias
CK1, EHK1, K1, KRT1A
Gene Description
keratin 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations
cytokeratin 1|epidermolytic hyperkeratosis 1|hair alpha protein|keratin, type II cytoskeletal 1
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