IGFBP3 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Cell lysate)
IGFBP3 MaxPab rabbit polyclonal antibody. Western Blot analysis of IGFBP3 expression in 293.
Western Blot (Transfected lysate)
Western Blot analysis of IGFBP3 expression in transfected 293T cell line (H00003486-T01) by IGFBP3 MaxPab polyclonal antibody.
Lane 1: IGFBP3 transfected lysate(31.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to IGFBP3 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IGFBP3 protein.
Immunogen
IGFBP3 (AAH64987.1, 1 a.a. ~ 291 a.a) full-length human protein.
Sequence
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
IGFBP3 MaxPab rabbit polyclonal antibody. Western Blot analysis of IGFBP3 expression in 293.Western Blot (Transfected lysate)
Western Blot analysis of IGFBP3 expression in transfected 293T cell line (H00003486-T01) by IGFBP3 MaxPab polyclonal antibody.
Lane 1: IGFBP3 transfected lysate(31.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to IGFBP3 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — IGFBP3
Entrez GeneID
3486GeneBank Accession#
NM_000598Protein Accession#
AAH64987.1Gene Name
IGFBP3
Gene Alias
BP-53, IBP3
Gene Description
insulin-like growth factor binding protein 3
Omim ID
146732Gene Ontology
HyperlinkGene Summary
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
IGF-binding protein 3|acid stable subunit of the 140 K IGF complex|binding protein 29|binding protein 53|growth hormone-dependent binding protein
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Interactome
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Pathway
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Disease
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Publication Reference
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G721-0282 exerts anxiolytic-like effects on chronic unpredictable mild stress in mice through inhibition of CHI3L1-mediated neuroinflammation.
Hyeon Joo Ham, Yong Sun Lee, Hee Pom Lee, Jaesung Cho, Young Wan Ham, Kwang Soo Lee, Jaesuk Yun, Sang Bae Han, Jin Tae Hong.
British Journal of Pharmacology 2021 Aug; 178(15):3079.
Application：WB-Ce, Mouse , BV-2 cells.
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G721-0282 exerts anxiolytic-like effects on chronic unpredictable mild stress in mice through inhibition of CHI3L1-mediated neuroinflammation.
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