HLA-DRA purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human HLA-DRA protein.
Immunogen
HLA-DRA (AAH32350, 1 a.a. ~ 254 a.a) full-length human protein.
Sequence
MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HLA-DRA MaxPab polyclonal antibody. Western Blot analysis of HLA-DRA expression in human spleen.Western Blot (Tissue lysate)
HLA-DRA MaxPab polyclonal antibody. Western Blot analysis of HLA-DRA expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of HLA-DRA expression in transfected 293T cell line (H00003122-T01) by HLA-DRA MaxPab polyclonal antibody.
Lane 1: HLA-DRA transfected lysate(28.05 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HLA-DRA
Entrez GeneID
3122GeneBank Accession#
BC032350Protein Accession#
AAH32350Gene Name
HLA-DRA
Gene Alias
HLA-DRA1
Gene Description
major histocompatibility complex, class II, DR alpha
Omim ID
142860Gene Ontology
HyperlinkGene Summary
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq
Other Designations
HLA class II histocompatibility antigen, DR alpha chain|MHC cell surface glycoprotein|histocompatibility antigen HLA-DR alpha
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Interactomes
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Pathways
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