FUT3 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FUT3 expression in transfected 293T cell line (H00002525-T02) by FUT3 MaxPab polyclonal antibody.
Lane 1: FUT3 transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human FUT3 protein.
Immunogen
FUT3 (NP_000140.1, 1 a.a. ~ 361 a.a) full-length human protein.
Sequence
MDPLGAAKPQWPWRRCLAALLFQLLVAVCFFSYLRVSRDDATGSPRAPSGSSRQDTTPTRPTLLILLWTWPFHIPVALSRCSEMVPGTADCHITADRKVYPQADTVIVHHWDIMSNPKSRLPPSPRPQGQRWIWFNLEPPPNCQHLEALDRYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWKPDSARVRYYQSLQAHLKVDVYGRSHKPLPKGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALDFCKACWKLQQESRYQTVRSIAAWFT
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FUT3 expression in transfected 293T cell line (H00002525-T02) by FUT3 MaxPab polyclonal antibody.
Lane 1: FUT3 transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — FUT3
Entrez GeneID
2525GeneBank Accession#
NM_000149.1Protein Accession#
NP_000140.1Gene Name
FUT3
Gene Alias
CD174, FT3B, FucT-III, LE, Les, MGC131739
Gene Description
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Omim ID
111100Gene Ontology
HyperlinkGene Summary
The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
Other Designations
Lewis FT|alpha-(1,3/1,4)-fucosyltransferase|blood group Lewis alpha-4-fucosyltransferase|fucosyltransferase 3|galactoside 3(4)-L-fucosyltransferase
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Interactome
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Pathway
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Disease
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