Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with AGER polyclonal antibody (Cat # PAB4296) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
OTTHUMP00000029155,OTTHUMP00000029156,advanced glycosylation end product-specific receptor RAGE3,advanced glycosylation end product-specific receptor variant sRAGE1,advanced glycosylation end product-specific receptor variant sRAGE2,receptor for advanced