CDC42 monoclonal antibody, clone 56a45
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Specifications
Product Description
Mouse monoclonal antibody raised against full length recombinant CDC42.
Immunogen
Recombinant protein corresponding to full length human CDC42.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes recombinant protein CDC42.
Form
Liquid
Purification
Affinity purification
Concentration
1 ug/uL
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis in CDC42 recombinant protein with CDC42 monoclonal antibody, clone 56a45 (Cat # MAB8796) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDC42
Entrez GeneID
998Protein Accession#
NM_044472.2Gene Name
CDC42
Gene Alias
CDC42Hs, G25K
Gene Description
cell division cycle 42 (GTP binding protein, 25kDa)
Omim ID
116952Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Other Designations
GTP-binding protein, 25kD|OTTHUMP00000002834|OTTHUMP00000002926|cell division cycle 42|cell division cycle 42 (GTP binding protein, 25kD)|cell division cycle 42 (GTP-binding protein, 25kD)|dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD))|d
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Interactomes
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Pathways
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Diseases
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