F9 monoclonal antibody, clone F9-1
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Specifications
Product Description
Mouse monoclonal antibody raised against F9.
Immunogen
Human F9.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Isotype
IgG1, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
Lyophilized from 10 mM PBS, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — F9
Entrez GeneID
2158Gene Name
F9
Gene Alias
FIX, HEMB, MGC129641, MGC129642, PTC
Gene Description
coagulation factor IX
Omim ID
306900Gene Ontology
HyperlinkGene Summary
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq
Other Designations
Christmas factor|OTTHUMP00000024154|coagulant factor IX|factor 9|factor IX|plasma thromboplastic component
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Interactomes
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Pathways
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Diseases
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