AKR1B10 rabbit monoclonal antibody
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Specifications
Product Description
Rabbit monoclonal antibody raised against a human AKR1B10 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AKR1B10 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AKR1B10 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AKR1B10
Entrez GeneID
57016GeneBank Accession#
AKR1B10Gene Name
AKR1B10
Gene Alias
AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI, MGC14103
Gene Description
aldo-keto reductase family 1, member B10 (aldose reductase)
Omim ID
604707Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq
Other Designations
aldo-keto reductase family 1, member B10|aldo-keto reductase family 1, member B11 (aldose reductase-like)|aldose reductase-like 1|aldose reductase-like peptide|aldose reductase-related protein|small intestine reductase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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AKR1B10 expression in benign prostatic hyperplasia and its related mechanism.
Wenjing Xu, Ya Gao, Jiaqi Zhang, Rong Zhang, Qihua Chen.
Oncology letters 2021 Sep; 22(3):683.
Application:IHC-P, Rat, Prostate.
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AKR1B10 expression in benign prostatic hyperplasia and its related mechanism.
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