ALDH4A1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
ALDH4A1 transfected lysate.
Western Blot
Lane 1: ALDH4A1 transfected lysate ( 61.7 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ALDH4A1 full-length
Host
Human
Theoretical MW (kDa)
61.7
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ALDH4A1 antibody (H00008659-B01) by Western Blots.
SDS-PAGE Gel
ALDH4A1 transfected lysate.
Western Blot
Lane 1: ALDH4A1 transfected lysate ( 61.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ALDH4A1
Entrez GeneID
8659GeneBank Accession#
NM_003748.2Protein Accession#
-Gene Name
ALDH4A1
Gene Alias
ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS
Gene Description
aldehyde dehydrogenase 4 family, member A1
Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000002544|OTTHUMP00000002545|P5C dehydrogenase|aldehyde dehydrogenase 4A1|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
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Interactome
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Pathway
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Disease
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