Immunoprecipitation of HLA-DOA transfected lysate using anti-HLA-DOA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with HLA-DOA purified MaxPab mouse polyclonal antibody (B02P) (H00003111-B02P).
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq
HLA-D0-alpha,MHC class II antigen,OTTHUMP00000029303,lymphocyte antigen,major histocompatibility complex, class II, DN alpha