This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CBL.
Quality Control Testing:
Standard curve using recombinant protein ( H00000867-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml.
Antibody pair set content: 1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-CBL (100 ug) 2. Detection antibody: mouse monoclonal anti-CBL, IgG1 Kappa (20 ug) *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq