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Last updated: 2014/4/14
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BIOtech
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AGT 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00000183-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-AGT full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 53.1
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-AGT antibody (H00000183-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00000183-T01
    AGT transfected lysate
    Western Blot
    QC Testing of H00000183-T01
    Lane 1: AGT transfected lysate ( 53.1 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 183
  • Gene Name:
  • AGT
  • Gene Alias:
  • ANHU,FLJ92595,FLJ97926,SERPINA8
  • Gene Description:
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Gene Summary:
  • The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035878,alpha-1 antiproteinase, antitrypsin,angiotensin I,angiotensin II,angiotensinogen,pre-angiotensinogen,serine (or cysteine) proteinase inhibitor
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