With the aid of micromanipulator, precise physical interactions, like single cell collection, injection, patch clamping, etc. under microscopic level becomes achievable. In general, depending on the application, one or more micromanipulators can be docked on a microscope stage to operate in microscopes field of view. A typical method for single cell collection is displayed including steps of cell aspiration and discharge. And, MMO-203 Three-axis Oil Hydraulic Micromanipulator from NARISHIGE Group is adopted here.