SLC1A2 recombinant monoclonal antibody, clone R02-1J4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SLC1A2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human SLC1A2.
Theoretical MW (kDa)
Calculated MW: 62 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
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Gene Info — SLC1A2
Entrez GeneID
6506Gene Name
SLC1A2
Gene Alias
EAAT2, GLT-1
Gene Description
solute carrier family 1 (glial high affinity glutamate transporter), member 2
Omim ID
600300Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
excitatory amino acid transporter 2|excitotoxic amino acid transporter 2|glial high affinity glutamate transporter|glutamate/aspartate transporter II|sodium-dependent glutamate/aspartate transporter 2|solute carrier family 1, member 2
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