DROSHA recombinant monoclonal antibody, clone R01-9I2
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human DROSHA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human DROSHA.
Theoretical MW (kDa)
Calculated MW: 159 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50-1:100)
Immunohistochemistry (1:50-1:100)
Immunofluorescence(1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — RNASEN
Entrez GeneID
29102Gene Name
RNASEN
Gene Alias
DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L
Gene Description
ribonuclease type III, nuclear
Omim ID
608828Gene Ontology
HyperlinkGene Summary
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM
Other Designations
drosha, double-stranded RNA-specific endoribonuclease|drosha, ribonuclease type III|nuclear RNase III Drosha|putative protein p241 which interacts with transcription factor Sp1|putative ribonuclease III|ribonuclease III, nuclear
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Interactome
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Disease
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