PARP1 recombinant monoclonal antibody, clone PARP-H8 (FITC)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of SK.N.MC cells unstained and untreated as negative control (blue) or untreated (red) or treated with staurosporine (green) and stained using Cleaved PARP (Asp214) antibody PARP-H8 FITC conjugate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PARP1.
Antibody Species
Rabbit
Immunogen
A synthetic peptide corresponding to residues surrounding Asp214 of human PARP
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of SK.N.MC cells unstained and untreated as negative control (blue) or untreated (red) or treated with staurosporine (green) and stained using Cleaved PARP (Asp214) antibody PARP-H8 FITC conjugate. -
Gene Info — PARP1
Entrez GeneID
142Protein Accession#
P09874Gene Name
PARP1
Gene Alias
ADPRT, ADPRT1, PARP, PARP-1, PPOL, pADPRT-1
Gene Description
poly (ADP-ribose) polymerase 1
Omim ID
173870Gene Ontology
HyperlinkGene Summary
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq
Other Designations
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)|ADP-ribosyltransferase NAD(+)|OTTHUMP00000035663|poly (ADP-ribose) polymerase family, member 1|poly(ADP-ribose) polymerase|poly(ADP-ribose) synthetase|poly(ADP-ribosyl)transferase
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Interactome
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Pathway
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Disease
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