INPPL1 recombinant monoclonal antibody, clone Ship2Y1135-1D2 (FITC)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of U937 cells untreated (red) or treated with INFa, IL-4 and pervanate (green) using Phospho-Ship2 (Tyr1135) (1D2) Rabbit mAb (FITC Conjugate) Ship2Y1135-1D2, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (FITC Conjugate) for cells untreated (black) or treated with IFNa, IL-4 and pervanadate (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human INPPL1.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr1135 of human phospho Ship2
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
Protein A purification, Protein G purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells untreated (red) or treated with INFa, IL-4 and pervanate (green) using Phospho-Ship2 (Tyr1135) (1D2) Rabbit mAb (FITC Conjugate) Ship2Y1135-1D2, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (FITC Conjugate) for cells untreated (black) or treated with IFNa, IL-4 and pervanadate (blue). -
Gene Info — INPPL1
Entrez GeneID
3636Protein Accession#
O15357Gene Name
INPPL1
Gene Alias
SHIP2
Gene Description
inositol polyphosphate phosphatase-like 1
Omim ID
600829Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq
Other Designations
51C protein
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Interactome
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Pathway
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Disease
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