NPM1 recombinant monoclonal antibody, clone NPMS4-A1
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More Files
- More Functions
Western Blot
Western blot analysis of extract from HeLa cells untreated or treated with nocodazole using Phospho-NPM (Ser4) antibody NPMS4-A1 at 01 ug/mL.
Flow Cytometry
Flow cytometric analysis of C6 cells untreated (red) or treated with nocodazole (green) using Phospho-NPM (Ser4) (A1) rabbit mAb NPMS4-A1 at 0.01 ug/mL, or concentration-matched rabbit (G9) mAb IgG Isotype for cells untreated (black) or treated with nocodazole (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NPM1.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser4 of human phospho-NPM
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.02% Sodium azide, 50% Glycerol, 0.1% BSA
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of extract from HeLa cells untreated or treated with nocodazole using Phospho-NPM (Ser4) antibody NPMS4-A1 at 01 ug/mL.Flow Cytometry
Flow cytometric analysis of C6 cells untreated (red) or treated with nocodazole (green) using Phospho-NPM (Ser4) (A1) rabbit mAb NPMS4-A1 at 0.01 ug/mL, or concentration-matched rabbit (G9) mAb IgG Isotype for cells untreated (black) or treated with nocodazole (blue). -
Gene Info — NPM1
Entrez GeneID
4869Protein Accession#
P06748Gene Name
NPM1
Gene Alias
B23, MGC104254, NPM
Gene Description
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Gene Ontology
HyperlinkGene Summary
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM
Other Designations
nucleolar phosphoprotein B23|nucleophosmin 1|nucleophosmin/nucleoplasmin family, member 1|numatrin
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Interactome
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Disease
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