DSC3 recombinant monoclonal antibody, clone R06-4G2
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human Desmocollin 3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human Desmocollin 3
Theoretical MW (kDa)
Calculated MW: 100 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Desmocollin 3 in K562, Hela lysates using human Desmocollin 3 recombinant monoclonal antibody, clone R06-4G2 (Cat # RAB01719).Immunocytochemistry
Immunocytochemical staining of Hela with Desmocollin 3 recombinant monoclonal antibody, clone R06-4G2 (Cat # RAB01719). (A) Desmocollin 3 (green) and (B) DAPI (blue). -
Gene Info — DSC3
Entrez GeneID
1825Protein Accession#
Q14574Gene Name
DSC3
Gene Alias
CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP
Gene Description
desmocollin 3
Omim ID
600271Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
desmocollin 4
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Interactome
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Disease
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