ADRB3 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of extract from mouse adipose tissue, using ADRB3 polyclonal antibody (Cat # PAB8502) .
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADRB3.
Immunogen
A synthetic peptide corresponding to human ADRB3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot analysis of extract from mouse adipose tissue, using ADRB3 polyclonal antibody (Cat # PAB8502) . -
Gene Info — ADRB3
Entrez GeneID
155Gene Name
ADRB3
Gene Alias
BETA3AR
Gene Description
adrenergic, beta-3-, receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq
Other Designations
Beta-3 Adrenergic Receptor
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Interactomes
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Pathways
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Diseases
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Publication Reference
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β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via β3AR-Dependent Protective Sphingosine-1 Phosphate Signaling.
Cannavo A, Rengo G, Liccardo D, Pun A, Gao E, George AJ, Gambino G, Rapacciuolo A, Leosco D, Ibanez B, Ferrara N, Paolocci N, Koch WJ.
Journal of the American College of Cardiology 2017 Jul; 70(2):182.
Application：WB, Mouse, Mouse cardiac lysates.
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Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy.
Trappanese DM, Liu Y, McCormick RC, Cannavo A, Nanayakkara G, Baskharoun MM, Jarrett H, Woitek FJ, Tillson DM, Dillon AR, Recchia FA, Balligand JL, Houser SR, Koch WJ.
Basic Research in Cardiology 2015 Jan; 110(1):456.
Application：WB-Ti, Mouse, Plasma membrane fraction, Myocardium, Myocytes, Liver.
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Beta3-adrenergic stimulation in the human heart: signal transduction, functional implications and therapeutic perspectives.
Pott C, Brixius K, Bloch W, Ziskoven C, Napp A, Schwinger RH.
Die Pharmazie 2006 Apr; 61(4):255.
Application：WB-Ti, Human, Human hearts.
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Structure and function of beta3-adrenergic receptors.
Skeberdis VA.
Medicina (Kaunas, Lithuania) 2004 Jan; 40(5):407.
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Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene.
Walston J, Silver K, Bogardus C, Knowler WC, Celi FS, Austin S, Manning B, Strosberg AD, Stern MP, Raben N, et al..
The New England Journal of Medicine 1995 Aug; 333(6):343.
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β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via β3AR-Dependent Protective Sphingosine-1 Phosphate Signaling.
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