KLK1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of KLK1.
Immunogen
A synthetic peptide corresponding to human KLK1.
Sequence
PNDECKKAHVQK
Host
Goat
Theoretical MW (kDa)
28.9
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
KLK1 polyclonal antibody (Cat # PAB7225) (0.5 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KLK1
Entrez GeneID
3816Protein Accession#
NP_002248.1Gene Name
KLK1
Gene Alias
KLKR, Klk6, hK1
Gene Description
kallikrein 1
Omim ID
147910Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq
Other Designations
glandular kallikrein 1|kallikrein 1, renal/pancreas/salivary|kallikrein serine protease 1|tissue kallikrein
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Interactome
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Disease
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Publication Reference
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Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats.
Montanari D, Yin H, Dobrzynski E, Agata J, Yoshida H, Chao J, Chao L.
Diabetes 2005 May; 54(5):1573.
Application:ELISA, Rat, Rat serum, urine.
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Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats.
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