COX6B1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human COX6B1.
Immunogen
Recombinant protein corresponding to human COX6B1.
Sequence
EDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFP
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human stomach with COX6B1 polyclonal antibody (Cat # PAB30684) shows strong cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of A-431 cells with COX6B1 polyclonal antibody (Cat # PAB30684) (Green) shows positivity in mitochondria. -
Gene Info — COX6B1
Entrez GeneID
1340Protein Accession#
P14854Gene Name
COX6B1
Gene Alias
COX6B, COXG
Gene Description
cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous)
Omim ID
124089Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq
Other Designations
cytochrome c oxidase subunit VIb|human cytochrome oxidase subunit VIb
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