AMHR2 polyclonal antibody
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AMHR2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human AMHR2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse testis tissue lysate (35 ug/lane) with AMHR2 polyclonal antibody (Cat # PAB2654). -
Gene Info — AMHR2
Entrez GeneID
269Protein Accession#
NP_065434;Q16671Gene Name
AMHR2
Gene Alias
AMHR, MISR2, MISRII
Gene Description
anti-Mullerian hormone receptor, type II
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
Mullerian inhibiting substance type II receptor
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Interactomes
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Pathways
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Diseases
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Publication Reference
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[Genetics and molecular pathology of anti-Mullerian hormone and its receptor].
Picard JY, Belville C.
J Soc Biol 2002 Jan; 196(3).
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Mullerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications.
Teixeira J, Maheswaran S, Donahoe PK.
Endocrine Reviews 2001 Oct; 22(5):657.
Application:WB-Ce, WB-Tr, Human, Cancers, Mammalian cells.
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Insensitivity to anti-mullerian hormone due to a mutation in the human anti-mullerian hormone receptor.
Imbeaud S, Faure E, Lamarre I, Mattei MG, di Clemente N, Tizard R, Carre-Eusebe D, Belville C, Tragethon L, Tonkin C, Nelson J, McAuliffe M, Bidart JM, Lababidi A, Josso N, Cate RL, Picard JY.
Nature Genetics 1995 Dec; 11(4):382.
Application:WB-Ti, WB-Tr, Hamster, Rabbit, CHO cells, Sertoli cells.
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[Genetics and molecular pathology of anti-Mullerian hormone and its receptor].
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