KTN1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with KTN1 polyclonal antibody (Cat # PAB21149) strong cytoplasmic positivity in glandular cells at 1:1000-1:2500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KTN1.
Immunogen
Recombinant protein corresponding to amino acids of human KTN1.
Sequence
ELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:1000-1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with KTN1 polyclonal antibody (Cat # PAB21149) strong cytoplasmic positivity in glandular cells at 1:1000-1:2500 dilution. -
Gene Info — KTN1
Entrez GeneID
3895Protein Accession#
Q86UP2Gene Name
KTN1
Gene Alias
CG1, KIAA0004, KNT, MGC133337, MU-RMS-40.19
Gene Description
kinectin 1 (kinesin receptor)
Omim ID
600381Gene Ontology
HyperlinkGene Summary
Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM
Other Designations
CG-1 antigen|OTTHUMP00000179010|OTTHUMP00000179011|OTTHUMP00000179012|kinectin 1|kinesin receptor
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Interactome
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Disease
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