CHRM1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CHRM1.
Immunogen
Recombinant protein corresponding to amino acids of human CHRM1.
Sequence
SETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with CHRM1 polyclonal antibody (Cat # PAB20697) shows strong cytoplasmic positivity in neuronal cells at 1:50-1:200 dilution. -
Gene Info — CHRM1
Entrez GeneID
1128Protein Accession#
P11229Gene Name
CHRM1
Gene Alias
HM1, M1, MGC30125
Gene Description
cholinergic receptor, muscarinic 1
Omim ID
118510Gene Ontology
HyperlinkGene Summary
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq
Other Designations
muscarinic acetylcholine receptor M1
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Interactome
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Disease
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