PRKAG1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded rat heart showing staining with PRKAG1 polyclonal antibody (Cat # PAB19812) at 1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PRKAG1.
Immunogen
A synthetic peptide corresponding to 15 amino acids at internal region of human PRKAG1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Recommend Usage
ELISA (1:5000-1:20000)
Immunohistochemistry (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of formalin-fixed paraffin-embedded rat heart showing staining with PRKAG1 polyclonal antibody (Cat # PAB19812) at 1:200 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRKAG1
Entrez GeneID
5571Protein Accession#
P54619Gene Name
PRKAG1
Gene Alias
AMPKG, MGC8666
Gene Description
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Omim ID
602742Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
5'-AMP-activated protein kinase, gamma-1 subunit|AMP-activated protein kinase, noncatalytic gamma-1 subunit|AMPK gamma-1 chain
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Interactome
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Pathway
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Disease
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