CCL11 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of CCL11.
Immunogen
A synthetic peptide corresponding to human CCL11.
Sequence
C-QDSMKYLDQKSPTPK
Host
Goat
Theoretical MW (kDa)
10.7
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CCL11
Entrez GeneID
6356Protein Accession#
NP_002977.1Gene Name
CCL11
Gene Alias
MGC22554, SCYA11
Gene Description
chemokine (C-C motif) ligand 11
Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq
Other Designations
eosinophil chemotactic protein|eotaxin|small inducible cytokine A11|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells.
Issa R, Sorrentino R, Sukkar MB, Sriskandan S, Chung KF, Mitchell JA.
Respiratory Research 2008 Apr; 9:30.
Application：ELISA, Human, Human airway smooth muscle cells.
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Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells.
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